Research Articles
How a Painkiller's Hidden Properties Shape Its Journey Through Your Body
Explore how pethidine's physicochemical properties influence its absorption and elimination in the human body, affecting pain management and safety.
The Two-Handed Drug: How Your Genes Determine Your Response to a Common Cold Medicine
Explore how CYP2D6 genetic polymorphism and stereoselectivity affect chlorpheniramine pharmacokinetics and individual drug responses.
The Forbidden Fruit: How Grapefruit Juice Turns Medication into a Double-Edged Sword
Explore the fascinating science behind how grapefruit juice dangerously interacts with medications like felodipine, increasing drug potency and side effects.
The Age-Dependent Journey of Nalbuphine: How Our Bodies Process Pain Medication Differently
Explore how age dramatically changes how our bodies process nalbuphine, from infants to elderly patients. Understand the pharmacokinetics behind safe pain medication dosing.
The Drug Detective Story: How a Radioactive Tag Revealed a Metabolic Surprise
Discover how scientists used radioactive carbon-14 to track a cancer drug's journey through the body and uncover unexpected metabolic pathways.
The Rise and Fall of Temafloxacin: A Pharmacokinetic Story
Explore the pharmacokinetic profile of temafloxacin, a fluoroquinolone antibiotic with excellent bioavailability but serious safety concerns that led to its withdrawal.
The Silent Hitchhiker: How a Pesticide Rides Through a Hen's Body
Exploring how the pesticide leptophos travels through a hen's body, causing delayed neurotoxicity and persistent damage in nerves and eggs.
The Mirror World Inside Your Medicine: How Chiral Chromatography Saves Lives
Exploring how chiral chromatography separates drug enantiomers to improve pharmacokinetics and prevent tragedies like thalidomide